The Diligent Observer Podcast

Episode 80: The Penn State Pipeline with Executive Director of Nittany Angels Joe Herbst

• Andrew Kazlow

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Today's episode explores three ideas that caught my attention:
â‘  Penn State has no shortage of research:
The opportunity is helping more of that research become successful commercial companies.
② University affiliation can create differentiated deal flow: Nittany Angels can invest in startups built around Penn State intellectual property as well as companies connected to Penn State founders, advisors, investors, and alumni across the country.
③ A fund and an angel network can work better together: Joe believes a hybrid structure can preserve the expertise and flexibility of an angel network while giving founders more certainty around how much capital they can actually raise.

My guest today is Joe Herbst, Executive Director of Nittany Angels, a new investor network focused on supporting the Penn State startup ecosystem.

Joe explains where angel capital fits between university research, technology licensing, early grants, and the point where a startup begins showing real product-market fit.

During our conversation, Joe shares:
• Why a $1.4 billion university research engine still needs angel investors.
• How Nittany Angels sits between university research and real product-market fit.
• Why Penn State’s 800,000+ alumni create a unique source of startup deal flow.
• How university IP can become investable companies instead of staying inside the lab.
• Why Nittany Angels prefers seed-stage companies with some market validation.
• How a university-affiliated angel network can unlock deals far beyond its local geography.
• Why combining an angel network with a fund can give founders more certainty around capital.
• How Penn State’s strengths in ag tech, materials science, and life sciences are creating startup opportunities.
• What a bedbug-elimination startup reveals about the value of practical university innovation.
• Why regional ecosystems can still attract outside capital when companies become compelling enough.

Connect with Joe:
LinkedIn

Connect with Andrew:
Newsletter | X | LinkedIn | Book | Website

Stuff We Reference:
Penn State
Nittany Angels
Invent Penn State
Penn State LaunchBox & Innovation Network
Penn State Entrepreneur-in-Residence Program
Garber Venture Capital Fund
Propel Business Seed Fund
Momentum Fund
Penn State Office of Technology Transfer
Penn State Research Foundation
Robin Hood Ventures
Angel Capital Association
SBIR / America’s Seed Fund
Ben Franklin Technology Partners
Penn State Smeal College of Business
Innovation Works — Pittsburgh Startup Ecosystem
Life Sciences Pennsylvania

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757 Angels fuels daring startups, connecting founders with incubation, acceleration, and capital infusion — from vision to venture.

The Aggie Angel Network is a 501(c)(3) nonprofit connecting accredited investors with early-stage, high-growth technology ventures—providing entrepreneurs with market expertise, mentorship, and strategic connections to transform promising ventures into successful companies.

Oregon Sports Angels is a non-profit, member-based organization made up of a diverse team of experienced sports, outdoor and fitness industry professionals, entrepreneurs, investors and do-gooders. Our mission is to find and help grow the next great sports & fitness product and service companies.

Nittany Angels connects accredited investors with Penn State-affiliated startups — providing capital, guidance, and community to help University-born innovations reach their full potential.

NuFund Venture Group is reshaping early-stage investing through a Founder-Fair approach and a nationally connected investor network that invests through a unique fund model.


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All opinions are personal and may not reflect the views of The Diligent Observer. Not investment advice. 

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